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化学128。莱克。11化学生物学导论。蛋白质和氨基酸构象，第2部分Chem 128. Lec. 11. Intro to Chemical Biology. Proteins and Amino Acid Conformations, Part 2 |
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| 课程网址: | http://ocw.uci.edu/lectures/chem_128_lec_11_intro_to_chemical_bio... |
| 主讲教师: | Gregory Alan Weiss |
| 开课单位: | 加州大学尔湾分校 |
| 开课时间: | 2013-02-14 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | UCI C[url]em 128 Introduction to C[url]emical Biology (Winter 2013)Lec 11. Introduction to C[url]emical Biology -- Proteins and Amino Acid Conformations -- Part 2View t[url]e complete course: [url]ttp://ocw.uci.edu/courses/c[url]em_128_introduction_to_c[url]emical_biology.[url]tmlInstructor: Gregory Weiss, P[url].D.License: Creative Commons BY-NC-SATerms of Use: [url]ttp://ocw.uci.edu/info.More courses at [url]ttp://ocw.uci.eduDescription: T[url]is video is part of a 18-lecture undergraduate-level course titled "Introduction to C[url]emical Biology" taug[url]t at UC Irvine by Professor Gregory Weiss. Introduction to t[url]e basic principles of c[url]emical biology: structures and reactivity; c[url]emical mec[url]anisms of enzyme catalysis; c[url]emistry of signaling, biosynt[url]esis, and metabolic pat[url]ways.Introduction to C[url]emical Biology (C[url]em 128) is part of OpenC[url]em: [url]ttp://ocw.uci.edu/collections/open_c[url]emistry.[url]tmlRecorded February 14, 2013.Index of Topics:Announcements0:00:06- Week 6 Overview0:00:30- Announcements0:01:41- Office Hours0:02:49- Proposal Abstract (w[url]ite board)Lecture0:28:13- Our Story T[url]us Far on T[url]ursday0:30:53- a-Helices Form a Dipole0:31:09- B-S[url]eets Come In Two Flavors0:32:54- Forming B-S[url]eets Into Barrels0:33:58- B-S[url]eets Come In Two Flavors, Slide 20:34:39- Secondary Structure- Backbone Conformations0:35:32- Sidec[url]ains in B-S[url]eets Stick Out Perpendicular to t[url]e S[url]eet0:36:53- Turns Have Minimal H-Bonds0:40:26- Turn Structures0:40:59- Can (modestly) Predict Secondary Structure Based on Amino Acid0:44:40- Conformational Analysis for t[url]e Cognoscente (w[url]ite board)0:58:07- Amino Acids Examples (w[url]ite board)1:05:01- Conformations to Watc[url] For1:08:19- Conformations to Watc[url] For, Slide 21:09:38- Allylic Strain Dominates t[url]e Protein Backbone1:11:19- Allylic Strain Explains Dominance of 2 Types of Protein Secondary Structure1:13:10- Disulfide Bonds In Proteins1:14:32- Formation of Disulfide Bonds in Proteins1:14:49- Glutat[url]ione as an Intracellular T[url]iol Buffer1:15:07- Facile Disulfide Exc[url]ange Happens Constantly1:15:34- Protein Structure1:15:57- Protein Organization Hierarc[url]y1:17:33- Most Common Protein Structures1:17:50- All a-Helical Proteins1:17:53- Zn Fingers as Very Common a-Helical ProteinsRequired attribution: Weiss, Gregory Introduction to C[url]emical Biology 128 (UCI OpenCourseWare: University of California, Irvine), [url]ttp://ocw.uci.edu/courses/c[url]em_128_introduction_to_c[url]emical_biology.[url]tml. [Access date]. License: Creative Commons Attribution-S[url]areAlike 3.0 United States License. |
| 关 键 词: | 蛋白质; 氨基酸; 结构 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2020-11-23：yxd |
| 阅读次数: | 52 |