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在细菌趋药性生化网络的鲁棒性和自适应能力

Robustness and Adaptation in Biochemical Networks of Bacterial Chemotaxis
课程网址: http://videolectures.net/sscs06_dasmahapatra_rabnb/  
主讲教师: Srinandan Dasmahapatra
开课单位: 南安普敦大学
开课时间: 2007-02-25
课程语种: 英语
中文简介:
所有生命形式都依靠信息处理来维持其高度组织化的状态。大分子和超分子结构是将生命系统与死亡物质区分开来的特殊属性的关键。本课程将采用工程学的角度介绍分子生物学(蛋白质,RNA,DNA)和理解分子机器在活细胞中运作所需的物理学(热力学,动力学,动力学)。在此基础上,将讨论分子水平的信息作用和处理 - 涵盖噪声,分子马达,构象转换和细胞内网络等主题 - 导致细胞决策(趋化性,发展)。在整个过程中,将探索从自然到人工系统的概念的潜在转移(稳健性,自我修复,纳米工程,分子计算)。
课程简介: All life forms rely on information processing to maintain their highly organised state. Macromolecules and supramolecular structures are key to the special properties that set living systems apart from dead matter. The course will adopt an engineering perspective to introduce the molecular biology (proteins, RNA, DNA) and the physics (thermodynamics, kinetics, dynamics) required for understanding the operation of the molecularmachinery at work in living cells. On this basis the role andthe processing of information at the molecular level will be discussed - covering topics such as noise, molecular motors, conformational switching and intracellular networks - leading to decision making in cells (chemotaxis, development). Throughout the course the potential transfer of concepts from nature to artificial systems will be explored (robustness, self-repair, nano-engineering, molecular computing).
关 键 词: 高度组织化; 分子生物学; 人工系统
课程来源: 视频讲座网
最后编审: 2020-10-14:yumf
阅读次数: 46