第7讲-细胞通讯与免疫学Lecture 7 - Cell Communication and Immunology |
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课程网址: | http://videolectures.net/yalebeng100s08_saltzman_lec07/ |
主讲教师: | W. Mark Saltzman |
开课单位: | 耶鲁大学 |
开课时间: | 2011-01-04 |
课程语种: | 英语 |
中文简介: | Saltzman教授谈到了细胞通讯,特别是配体-受体相互作用,这对维持体内平衡非常重要。讨论了不同类型的受体和配体、它们相互作用的性质以及将其应用于药物开发的方法(例如,羟多巴、的士莫芬、β受体阻滞剂)。接下来,Saltzman教授将讨论激酶、磷酸酶、环AMP和蛋白质状态转换的机制。介绍了三类细胞通讯信号:自分泌、旁分泌和内分泌。最后,给出了一个利用血糖水平调节/响应进行细胞通信的示例。 |
课程简介: | Professor Saltzman talks about cell communication, specifically ligand-receptor interactions that are important in maintaining homeostasis in the body. Different types of receptors and ligands, the nature of their interactions and ways to apply this into developing drugs are discussed (eg. Aldopa, Taximofen, beta-blockers). Next, Professor Saltzman talks about kinases, phosphatases, cyclic AMP and the mechanism of switching protein states. Three categories of cell communication signals are introduced: autocrine, paracrine, and endocrine. Finally, an example of cell communication using regulation/response to blood sugar level is presented. |
关 键 词: | 细胞通讯; 配体-受体; 内分泌 |
课程来源: | 视频讲座网 |
数据采集: | 2021-11-28:zkj |
最后编审: | 2021-11-28:zkj |
阅读次数: | 72 |