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7.340 避免基因组不稳定性：DNA复制、细胞周期和癌症
7.340 Avoiding Genomic Instability: DNA Replication, the Cell Cycle, and Cancer |
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| 课程网址: |
http://ocw.mit.edu/courses/biology/7-340-avoiding-genomic-instabi...
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| 主讲教师: |
Dr. John Randell ; Dr. Robyn Tanny
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| 开课单位: |
麻省理工学院
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| 开课时间: |
信息不详。欢迎您在右侧留言补充。
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| 课程语种: |
英语
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| 中文简介: |
在这门课中，我们将学习在整个细胞周期中DNA复制的过程是如何被调控的，以及当DNA复制出错时会发生什么。细胞如何知道何时何地开始复制DNA?一个细胞如何防止它的DNA被复制不止一次?受损的DNA如何导致细胞停止DNA复制直到损伤被修复?基因组的复制如何与其他基本过程协调?我们将检查来自科学文献的经典和最新论文，以提供这些问题的答案，并获得生物学家如何处理这些问题的见解。这门课程是麻省理工学院生物系提供的许多高等本科生研讨会之一。这些研讨会是为有兴趣利用初级研究文献在高度互动的环境中讨论和学习当前生物研究的学生而设计的。许多本科生高级研讨会的讲师都是对教学有浓厚兴趣的博士后科学家。
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| 课程简介: |
In this class we will learn about how the process of DNA replication is regulated throughout the cell cycle and what happens when DNA replication goes awry. How does the cell know when and where to begin replicating its DNA? How does a cell prevent its DNA from being replicated more than once? How does damaged DNA cause the cell to arrest DNA replication until that damage has been repaired? And how is the duplication of the genome coordinated with other essential processes? We will examine both classical and current papers from the scientific literature to provide answers to these questions and to gain insights into how biologists have approached such problems. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
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| 关 键 词: |
细胞; 遗传物质; 细胞死亡; 肿瘤发生; 突变; 基因; DNA复制; 细胞周期; 受损的DNA; 基因组; 肿瘤形成; 抗癌药物; 病毒; 细胞控制
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| 课程来源: |
麻省理工学院公开课
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| 最后编审: |
2017-11-26：cmh
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| 阅读次数: |
22
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