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磁共振成像(MRI)与超极化C-13和He-3造影剂的方法和应用

Methodology and applications of magnetic resonance imaging (MRI) with hyperpolarized C-13 and He-3 contrast agents
课程网址: http://videolectures.net/kolokviji_fain_methodology/  
主讲教师: Sean Fain
开课单位: 威斯康星大学
开课时间: 2011-11-18
课程语种: 英语
中文简介:
最近在惰性气体和固态生物活性化合物(例如13C-丙酮酸盐)的极化方面的创新使得MRI的新应用能够用于研究诸如肺通气和癌症代谢的功能参数。 这些方法对采集速度和射频线圈灵敏度提出了更高的要求,以便解决这些因子的非平衡自旋晶格(T1)衰减和信号检测问题的多核性质,例如, 依次或同时成像常规质子和极化核。 本讲座将介绍使用双调谐线圈设计和快速MRI方法改善偏振水平和图像质量的偏振方法和方法。 将介绍极化MRI在肺功能和代谢研究中的几种应用
课程简介: Recent innovations in polarization of noble gases and solid state biologically active compounds such as 13C-pyruvate have enable new applications of MRI for the study of functional parameters such as lung ventilation and cancer metabolism. These methods have put increase demands on acquisition speed and rf-coil sensitivity in order to address the non-equilibrium spin-lattice (T1) decay of these agents and multi-nuclear nature of the signal detection problem, e.g. imaging conventional proton and the polarized nucleus either sequentially or simultaneously. This talk will introduce the methodology behind polarization and methods to improve polarization levels and image quality using dual-tuned coil designs and fast MRI methods. Several applications of polarized MRI to study lung function and metabolism will be presented.
关 键 词: 固态生物活性化合物; 射频线圈灵敏度; 多核性质
课程来源: 视频讲座网
最后编审: 2020-07-14:yumf
阅读次数: 125