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蛋白质折叠与人类疾病

Protein Folding And Human Disease
课程网址: https://ocw.mit.edu/courses/7-88j-protein-folding-and-human-disea...  
主讲教师: Prof. Jonathan King
开课单位: 麻省理工学院
开课时间: 2015-01-01
课程语种: 英语
中文简介:
本课程涵盖蛋白质折叠、错误折叠、淀粉样蛋白聚合和聚集的氨基酸序列控制。阅读和讨论的主题包括伴侣的结构和功能、纤维蛋白的折叠和组装,以及与阿尔茨海默氏症、帕金森氏症、亨廷顿氏症和其他蛋白质沉积疾病中蛋白质错误折叠和聚集相关的病理学。学生需要撰写并提交一篇研究论文。
课程简介: This course covers amino acid sequence control of protein folding, misfolding, amyloid polymerization and aggregation. Readings and discussions address topics such as chaperone structure and function, folding and assembly of fibrous proteins, and pathologies associated with protein misfolding and aggregation in Alzheimer’s, Parkinson’s, Huntington’s and other protein deposition diseases. Students are required to write and present a research paper. 
关 键 词: 蛋白质折叠; 人类疾病; 氨基酸序列控制
课程来源: 麻省理工学院公开课
数据采集: 2024-04-02:chenjy
最后编审: 2024-04-02:chenjy
阅读次数: 10