图 书 馆
生物动力系统中的一致性原理Consistency Principle in Biological Dynamical Systems |
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| 课程网址: | http://videolectures.net/eccs07_kaneko_cpb/ |
| 主讲教师: | Kunihiko Kaneko |
| 开课单位: | 东京大学 |
| 开课时间: | 2007-11-29 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | We propose consistency principle between different levels, to understand a biological system. Three topics are discussed. First, as a result of consistency between molecule replication and cell reproduction, universal statistical laws on chemical abundances over cells are derived as also confirmed experimentally. They include power-law distribution of gene expressions,log-normal distribution of chemical abundances over cells, and embedding of the power law into the network connectivity. Second, as a result of consistency between gene and phenotype,a general relationship between phenotype fluctuations by genetic variation and isogenic phenotypic fluctuation by developmental noise is derived. Third, we touch upon the chaos mechanism for stem cell differentiation with autonomous regulation, as a result of consistency of cell reproduction and growth of cell ensemble. |
| 关 键 词: | 生物动力系统; 分子复制; 细胞繁殖 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2021-01-31：nkq |
| 阅读次数: | 35 |