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应变演化与疾病动力学的耦合The coupling of strain evolution and disease dynamics |
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| 课程网址: | http://videolectures.net/ephdcs08_wieland_tcoseadd/ |
| 主讲教师: | Stefan Wieland |
| 开课单位: | Gulbenkian科学研究所 |
| 开课时间: | 2008-10-15 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | Influenza A is characterized by seasonal outbreaks and a gradual genetic, yet discontinuous antigenic evolution (antigenic "cluster jumps" occuring every 4-7 years, with a large seasonal epidemic as a result of lacking immunity among the population).The interplay between viral mutations and an age-group-specific human immune response is modelled here, trying to account for the observed phenomena and to predict next season's epidemic strain from the dynamics of the previous year. |
| 关 键 词: | 生物学; 免疫; 疾病动力学 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2019-12-05：lxf |
| 阅读次数: | 45 |