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生物信息学的优化与应用

Optimization and Applications in Bioinformatics
课程网址: http://videolectures.net/prib2010_dhaenens_oaab/  
主讲教师: Clarisse Dhaenens
开课单位: 里尔理工学院
开课时间: 2010-10-14
课程语种: 英语
中文简介:
大多数生物信息学问题都涉及大变量集的操作。因此,寻找这些变量的良好组合需要先进的搜索机制。本教程的目的是提供有关如何使用组合优化来帮助应对生物信息学挑战的提示。本教程的第一部分将致力于组合优化领域。它将着重于关键概念(问题的模型化、目标函数的定义、约束的确定),并将提出一些经典的解决方法,包括精确方法和元启发式(如遗传算法)。本教程的第二部分将介绍一些应用程序。它将通过不同的生物信息学问题说明组合优化方法是如何成功应用的。
课程简介: Most of bioinformatics problems deal with the manipulation of large sets of variables. Hence, looking for a good combinaisons of these variables requires advanced search mechanisms. The aim of this tutorial is to provide hints on how to use combinatorial optimization to help with bioinformatics challenges. The first part of the tutorial will be dedicated to the combinatorial optimization domain. It will focuss on the key concepts (modelization of problems, definition of the objective function, determination of the constraints) and will present some classical solution methods including exact methods and metaheuristics such as genetic algorithms. The second part of the tutorial will present some applications. It will illustrate through different bioinformatics problems, how combinatorial optimization approaches have been applied with success.
关 键 词: 生物信息学; 组合优化; 遗传算法
课程来源: 视频讲座网
最后编审: 2020-06-12:yumf
阅读次数: 66