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宏基因组的计算分析

Computational Analysis of Metagenomes
课程网址: http://videolectures.net/prib2010_huson_caom/  
主讲教师: Daniel Huson
开课单位: 蒂宾根大学
开课时间: 2010-10-14
课程语种: 英语
中文简介:
下一代测序技术的投入和成本效率的持续改进推动了元基因组学项目的数量和范围的快速增长,该项目旨在在土壤、水、肠道、古骨和人类生物群落等多种环境中通过测序研究微生物联盟。元基因组学的前三个计算挑战是:(1)分类分析,谁在那里?(2)功能分析,他们在做什么?(3)不同的元基因组如何比较,它们的差异与环境差异是否相关?本文将介绍元基因组学,并将讨论为解决这三个挑战而开发的一些方法。元基因组学是一个非常成长的领域,需要做很多工作来支持元基因组数据集的分析。
课程简介: Continuing improvements in the through-put and cost efficiency of next generation sequencing technologies are fueling a rapid increase in the number and scope of metagenomics projects, which aim at studying consortia of microbes by sequencing, in environments as diverse as soil, water, gut, ancient bones and the human biome. The first three computational challenges in metagenomics are: (1) Taxonomic analysis, who is out there? (2) Functional analysis, what are they doing? (3) How do different metagenomes compare and are their differences correlated to environmental differences? This talk will give an introduction to metagenomics and will discuss some of the methods that have be developed to address these three challenges. Metagenomics is a very growing field and much work needs to be done to support the analysis of metagenomic datasets.
关 键 词: 成本效率; 宏基因组; 数据分析
课程来源: 视频讲座网
最后编审: 2020-06-03:毛岱琦(课程编辑志愿者)
阅读次数: 55