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生物材料 - 组织相互作用

Biomaterials-Tissue Interactions
课程网址: http://ocw.mit.edu/courses/biological-engineering/20-441j-biomate...  
主讲教师: Prof. Ioannis Yannas; Prof. Myron Spector
开课单位: 麻省理工学院
开课时间: 信息不详。欢迎您在右侧留言补充。
课程语种: 英语
中文简介:
本课程介绍了材料科学和细胞生物学的基本原理,这些原理是医疗植入物、人工器官和组织工程基质设计的基础。主题包括生物材料的表面特征和蛋白质在生物材料上吸附的分析方法。分子和细胞与生物材料的相互作用从单细胞过程,如基质合成、降解和收缩等方面进行分析。它还涵盖了植入不同器官后伤口愈合和组织重塑的机制。其他领域包括组织和器官再生;基于生物材料与组织相互作用控制的植入物和假体设计;参考案例研究对完整、可生物降解和可生物替换的植入物进行比较分析。还讨论了恢复组织和器官生理功能的标准。
课程简介: This course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Also addressed are criteria for restoration of physiological function for tissues and organs.
关 键 词: 生物材料; 细胞生物学; 医疗植入物; 人造器官
课程来源: 信息不详。欢迎您在右侧留言补充。
最后编审: 2017-03-31:lkn
阅读次数: 38