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7.340免疫逃避:如何隐藏病原体避免主体监控

7.340 Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance
课程网址: http://ocw.mit.edu/courses/biology/7-340-immune-evasion-how-sneak...  
主讲教师: Dr. Dina Gould Halme
开课单位: 麻省理工学院
开课时间: 信息不详。欢迎您在右侧留言补充。
课程语种: 英语
中文简介:
每一次感染都是入侵病原体和抵抗宿主之间的战斗。为了成功,一种病原体必须逃离宿主免疫系统的许多防御,直到它能够复制并传播到另一个宿主。病原体必须阻止免疫功能的三个阶段之一:检测、激活或效应器功能。讨论了疾病特异性免疫逃避的例子以及病原体战胜宿主免疫系统的机制。同时考虑到这些宿主-病原体相互作用揭示了免疫系统的正常功能和基本的细胞生物学过程,如蛋白质成熟和降解。
课程简介: Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation.
关 键 词: 免疫系统; 病原体; 表面受体; 细胞裂解
课程来源: 信息不详。欢迎您在右侧留言补充。
最后编审: 2017-04-01:lkn
阅读次数: 31