HST.512 基因组医学HST.512 Genomic Medicine |
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课程网址: | http://ocw.mit.edu/courses/health-sciences-and-technology/hst-512... |
主讲教师: | Prof. Isaac Kohane(Course Director) |
开课单位: | 麻省理工学院 |
开课时间: | 2004-01-01 |
课程语种: | 英语 |
中文简介: | 本课程回顾了关键的基因组技术和计算方法,这些技术正推动着预后、诊断和治疗的进展。整个学期,重点将回到围绕医学基因组学背景的问题上,包括:医生需要知道什么?患者可能会遇到哪些问题?他/她应该如何回应?讲师将引导学生通过真实的病患-医生互动。结果考虑和社会经济影响的个性化医学也进行了讨论。课程的第一部分介绍了分子生物学、计算生物学和基因组学的关键基本概念。继续本课程的信息学应用部分,讲师在每一个讲习班开始时都有一个场景,目的是通过展示:为什么知道这一点很重要?所提供的信息将如何影响医疗实践?最后一部分介绍了基因组医学的伦理、法律和社会问题。在一个与学生讨论的论坛上,我们向他们展示了基因组医学与预防保健和公共卫生的关系:你现在的准备程度如何?医疗保健行业必须面对哪些挑战才能达到其所需的目标?讲师:Atul J.Butte博士Steven A.Greenberg博士Alvin Thong Juak Kho博士Peter Park博士Marco F.Ramoni博士Alberto A.Riva博士Zoltan Szallasi博士Jeffrey Mark Drazen博士Todd Golub博士Joel Hirschhorn博士Greg Tucker Kellogg博士Scott Weiss博士 |
课程简介: | This course reviews the key genomic technologies and computational approaches that are driving advances in prognostics, diagnostics, and treatment. Throughout the semester, emphasis will return to issues surrounding the context of genomics in medicine including: what does a physician need to know? what sorts of questions will s/he likely encounter from patients? how should s/he respond? Lecturers will guide the student through real world patient-doctor interactions. Outcome considerations and socioeconomic implications of personalized medicine are also discussed. The first part of the course introduces key basic concepts of molecular biology, computational biology, and genomics. Continuing in the informatics applications portion of the course, lecturers begin each lecture block with a scenario, in order to set the stage and engage the student by showing: why is this important to know? how will the information presented be brought to bear on medical practice? The final section presents the ethical, legal, and social issues surrounding genomic medicine. A vision of how genomic medicine relates to preventative care and public health is presented in a discussion forum with the students where the following questions are explored: what is your level of preparedness now? what challenges must be met by the healthcare industry to get to where it needs to be? Lecturers Dr. Atul J. Butte Dr. Steven A. Greenberg Dr. Alvin Thong-Juak Kho Dr. Peter Park Dr. Marco F. Ramoni Dr. Alberto A. Riva Dr. Zoltan Szallasi Dr. Jeffrey Mark Drazen Dr. Todd Golub Dr. Joel Hirschhorn Dr. Greg Tucker-Kellogg Dr. Scott Weiss |
关 键 词: | 基因组医学; 生物芯片; 计算生物学; 机器学习; 药物基因组学; 个体药理学; 肿瘤诊断; 遗传病; 生物医学 |
课程来源: | 麻省理工学院公开课 |
最后编审: | 2024-06-26:chenjy |
阅读次数: | 48 |