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7.344 肿瘤抑制基因p53：我们基因组的监护人如何预防癌症（麻省理工学院）7.344 Tumor Suppressor Gene p53: How the Guardian of our Genome Prevents Cancer (MIT) |
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| 课程网址: | http://ocw.mit.edu/courses/biology/7-344-tumor-suppressor-gene-p5... |
| 主讲教师: | Dr. Wen Xue |
| 开课单位: | 麻省理工学院 |
| 开课时间: | 信息不详。欢迎您在右侧留言补充。 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | Cancer is a leading cause of death worldwide. Cancer involves uncontrolled cell growth, resistance to cell death, failure to differentiate into a particular cell type, and increased cellular motility. A family of gate-keeper genes, known as tumor suppressor genes, plays important roles in preventing the initiation and progression of cancer. Among these, p53 is the most famous. Because of its essential role in maintaining genomic integrity, p53 is often called the guardian of the genome. During this course, we will study how p53 serves as a pivotal tumor suppressor gene in preventing cancer.This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. |
| 关 键 词: | 肿瘤抑制基因; p53蛋白; 肿瘤; 细胞生长信号; 细胞周期调控; DNA损伤; DNA修复; 程序性细胞死亡; 凋亡; 基因组完整性; 癌基因 |
| 课程来源: | 麻省理工学院公开课 |
| 最后编审: | 2017-11-26：cmh |
| 阅读次数: | 45 |