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基因组重排算法的双切割和加入

Algorithms for Genome Rearrangement by Double Cut and Join
课程网址: http://videolectures.net/algo2012_stoye_genome_rearrangement/  
主讲教师: Jens Stoye
开课单位: 比勒费尔德大学
开课时间: 信息不详。欢迎您在右侧留言补充。
课程语种: 英语
中文简介:
以基因顺序为基础的基因组进化已经通过各种重排操作，如逆序、易位、转位、闭塞互换、融合和裂变来建模。Yancopoulos等人(2005)引入的双切割和连接(double cut and join, DCJ)操作允许对所有这些经典操作建模，同时允许使用非常简单的算法，而以前的算法用于更受限制的模型。在这篇演讲中，我们展示了几个基于DCJ模型的基因组重排算法的结果，并解决了一些有趣的数学建模问题。
课程简介: Genome evolution on the basis of gene order has been modeled by a variety of rearrangement operations such as inversions, translocations, transpositions, block interchanges, fusions and fissions. The double cut and join (DCJ) operation, introduced by Yancopoulos et al. (2005), allows to model all these classical operations while allowing for very simple algorithms, compared to earlier ones for more restricted models. In this talk, we present several of our algorithmic results related to genome rearrangement based on the DCJ model and also address some interesting mathematical modeling questions.
关 键 词: 基因组; 重排; 切割
课程来源: 视频讲座网
最后编审: 2019-10-30：cwx
阅读次数: 82

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