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基因调控网络分段仿射模型的层次分析

Hierarchical Analysis of Piecewise Affine Models of Gene Regulatory Networks
课程网址: http://videolectures.net/eccs07_tournier_hap/  
主讲教师: Laurent Tournier
开课单位: INRIA研究机构
开课时间: 2007-11-27
课程语种: 英语
中文简介:
本文提出了一种分层组织某类分段仿射微分系统的方法。这类动力学系统为基因调控网络的建模提供了一个良好的框架,近年来得到了广泛的研究。利用分段仿射系统的层次结构,通过对几个较小的子系统的分析,定性地分析了整个系统的渐近行为。针对这些网络,提出了一种阈值消除算法,在特定情况下对层次分解进行细化,从而提高了分析能力。
课程简介: We propose in this paper a method to hierarchically organize a certain type of piecewise affine differential system. This specific class of dynamical systems has been extensively studied for the past few years, as it provides a good framework to model gene regulatory networks. Using the hierarchical organization of a piecewise affine system, we present a technique to qualitatively analyze the asymptotic behavior of the whole system thanks to the analysis of several smaller subsystems. Specifically adapted to these networks, an algorithm of threshold elimination is presented, that refines in certain cases the hierarchical decomposition and therefore improves the analysis.
关 键 词: 遗传学; 基因调控; 仿射微分系统; 阈值消除算法
课程来源: 视频讲座网
最后编审: 2021-01-08:yumf
阅读次数: 101