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高维共线数据的双向分析

Two-Way Analysis of High-Dimensional Collinear Data
课程网址: http://videolectures.net/ecmlpkdd09_huopaniemi_twahdcd/  
主讲教师: Ilkka Huopaniemi
开课单位: 阿尔托大学
开课时间: 2009-10-20
课程语种: 英语
中文简介:
我们提出了贝叶斯模型,用于高维,小样本数据集的双向ANOVA类型分析,具有高度相关的变量组。现代蜂窝测量方法是主要的应用领域;通常,任务是患病和健康样本之间的差异分析,并且需要多途径分析的额外协变量使其复杂化。主要的复杂因素是高维度和低样本量的结合,这使得经典的多变量技术变得毫无用处。我们引入了一种层次模型,通过假设输入变量具有相似的行为组来进行维数降低,并对该组降维潜在变量执行ANOVA类型分解。我们应用这些方法来研究最近的大型队列人类糖尿病研究的脂质组学谱。
课程简介: We present a Bayesian model for two-way ANOVA-type analysis of high-dimensional, small sample-size datasets with highly correlated groups of variables. Modern cellular measurement methods are a main application area; typically the task is differential analysis between diseased and healthy samples, complicated by additional covariates requiring a multi-way analysis. The main complication is the combination of high dimensionality and low sample size, which renders classical multivariate techniques useless. We introduce a hierarchical model which does dimensionality reduction by assuming that the input variables come in similarly-behaving groups, and performs an ANOVA-type decomposition for the set of reduced-dimensional latent variables. We apply the methods to study lipidomic profiles of a recent large-cohort human diabetes study.
关 键 词: 贝叶斯模型; 小样本数据集; 现代蜂窝测量
课程来源: 视频讲座网
最后编审: 2019-03-24:cwx
阅读次数: 74