图 书 馆
用高斯过程分析基因表达数据Analysing Gene Expression Data Using Gaussian Processes |
|
| 课程网址: | http://videolectures.net/gpip06_wernisch_agedu/ |
| 主讲教师: | Lorenz Wernisch |
| 开课单位: | 伦敦大学学院 |
| 开课时间: | 2007-02-25 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | Complex gene regulatory mechanisms ensure the proper functioning of biological cells. New high-throughput experimental techniques, such as microarrays, provide a snapshot of gene expression levels of thousands of genes at the same time. If repeated on a sample of synchronized cells, time-series profiles of gene activity can be obtained. The aim is to reconstruct the complex gene regulatory network underlying these profiles. Genes often influence each other in a nonlinear fashion and with intricate interaction patterns. Linear models are often unsuited to capture such relationships. Gaussian processes, on the other hand, are ideal for representing nonlinear relationships. A particular attraction is the automatic relevance determination effect, removing unused inputs and resulting in sparse gene networks. |
| 关 键 词: | 基因调控; 生物细胞; 高通量 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2020-10-22：chenxin |
| 阅读次数: | 64 |