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蛋白质通道和纳米孔大分子输运理论Theory of macromolecular transport through protein channels and nanopores |
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| 课程网址: | http://videolectures.net/kolokviji_muthukumar_macromolecular_tran... |
| 主讲教师: | Murugappan Muthukumar |
| 开课单位: | 马萨诸塞大学 |
| 开课时间: | 2012-11-05 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | An understanding of the ubiquitous phenomenon of translocation of electrically charged macromolecules through narrow channels requires an adequate description of polyelectrolyte dynamics, electrolyte dynamics, and hydrodynamics, and the confinement effects from the charge-decorated pores. The biophysics of polyelectrolyte translocation process will be discussed using concepts from polyelectrolyte physics and electrophysiology, against a background of single-molecule experiments. Specifically, the capture and threading of DNA/RNA and proteins through alpha-hemolysin channels and solid-state nanopores under an external electric field, and DNA ejection in bacteriophages will be discussed.. |
| 关 键 词: | 聚电解质动力学; 单分子实验; α溶血素 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2020-07-13：yumf |
| 阅读次数: | 82 |