图 书 馆
高阶多任务特征学习识别阿尔茨海默病进展预测的纵向表型标记High-Order Multi-Task Feature Learning to Identify Longitudinal Phenotypic Markers for Alzheimer Disease Progression Prediction |
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| 课程网址: | http://videolectures.net/nips2012_wang_alzheimer_disease/ |
| 主讲教师: | Hua Wang |
| 开课单位: | 科罗拉多矿业学院 |
| 开课时间: | 2013-01-16 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | Alzheimer disease (AD) is a neurodegenerative disorder characterized by progressive impairment of memory and other cognitive functions. Regression analysis has been studied to relate neuroimaging measures to cognitive status. However, whether these measures have further predictive power to infer a trajectory of cognitive performance over time is still an under-explored but important topic in AD research. We propose a novel high-order multi-task learning model to address this issue. The proposed model explores the temporal correlations existing in data features and regression tasks by the structured sparsity-inducing norms. In addition, the sparsity of the model enables the selection of a small number of MRI measures while maintaining high prediction accuracy. The empirical studies, using the baseline MRI and serial cognitive data of the ADNI cohort, have yielded promising results. |
| 关 键 词: | 回归分析; 神经影像学; 认知表现 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2019-09-07：lxf |
| 阅读次数: | 102 |