0


检测人体和模型生物体对实验因素的类似高维反应

Detecting similar high-dimensional responses to experimental factors from human and model organism
课程网址: http://videolectures.net/nipsworkshops2011_suvitaival_organism/  
主讲教师: Tommi Suvitaival
开课单位: 阿尔托大学
开课时间: 2012-01-23
课程语种: 英语
中文简介:
我们提出了一个贝叶斯模型,用于分析多个实验因素在两个物种研究中的效果,而不需要先验已知的匹配。从人类疾病的模型研究,使用*组学技术和各种模式生物进行,问题出现了:是否有类似的东西在某些条件下,不同生物的分子反应,如健康与患病?我们的方法为分析多物种数据的任务提供了生成模型,自然地考虑了关于性别,年龄,治疗或疾病状态等影响因素的额外信息。
课程简介: We present a Bayesian model for analysing the effect of multiple experimental factors in two-species studies without the requirement of a priori known matching. From model studies of human diseases, conducted using *omics technologies and various model organisms, the question emerges: is there something similar in the molecular responses of the different organisms under certain conditions, such as healthy vs. diseased? Our approach provides a generative model for the task of analysing multi-species data, naturally taking into account the additional information about the affecting factors such as gender, age, treatment, or disease status.
关 键 词: 贝叶斯模型; 分子反应; 生成模型
课程来源: 视频讲座网
最后编审: 2019-09-07:lxf
阅读次数: 32