图 书 馆
细菌趋化过程中细胞内信号的时空模拟Spatiotemporal Modelling of Intracellular Signalling in Bacterial Chemotaxis |
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| 课程网址: | http://videolectures.net/pesb07_tindall_sib/ |
| 主讲教师: | Marcus J. Tindall |
| 开课单位: | 牛津大学 |
| 开课时间: | 2007-04-04 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | Whilst theoretical models have been used to understand aspects of bacterial chemotaxis systems for the past thirty or so years, little work has focused on the importance that spatial localisation of proteins within the cytoplasm of the cell has on the overall functionality of the intracellular network. In this talk we will examine spatio-temporal models of signal transduction developed to describe the phosphotransfer pathway within E. coli. This model framework will then be extended to examine the importance of protein localisation within R. sphaeroides, a species which contains considerably more phosphotransfer proteins than E. coli and the spatial localisation of which plays a particularly important role in activating certain elements of the phosphotransfer network. The difficulties encountered in obtaining robust parameter estimates for reaction rates within the R. sphaeroides will also be detailed. Joint work with S. L. Porter, P. K. Maini and J. P. Armitage. |
| 关 键 词: | 细菌趋化; 细胞质; 蛋白质 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2019-09-13：lxf |
| 阅读次数: | 26 |