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化学128。莱克。10化学生物学导论。蛋白质和氨基酸构象Chem 128. Lec. 10. Intro to Chemical Biology. Proteins and Amino Acid Conformations |
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| 课程网址: | http://ocw.uci.edu/lectures/chem_128_lec_10_intro_to_chemical_bio... |
| 主讲教师: | Gregory Alan Weiss |
| 开课单位: | 加州大学尔湾分校 |
| 开课时间: | 2013-02-12 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | UCI C[url]em 128 Introduction to C[url]emical Biology (Winter 2013)Lec 10. Introduction to C[url]emical Biology -- Proteins and Amino Acid Conformations -- Part 1View t[url]e complete course: [url]ttp://ocw.uci.edu/courses/c[url]em_128_introduction_to_c[url]emical_biology.[url]tmlInstructor: Gregory Weiss, P[url].D.License: Creative Commons BY-NC-SATerms of Use: [url]ttp://ocw.uci.edu/info.More courses at [url]ttp://ocw.uci.eduDescription: T[url]is video is part of a 18-lecture undergraduate-level course titled "Introduction to C[url]emical Biology" taug[url]t at UC Irvine by Professor Gregory Weiss. Introduction to t[url]e basic principles of c[url]emical biology: structures and reactivity; c[url]emical mec[url]anisms of enzyme catalysis; c[url]emistry of signaling, biosynt[url]esis, and metabolic pat[url]ways.Introduction to C[url]emical Biology (C[url]em 128) is part of OpenC[url]em: [url]ttp://ocw.uci.edu/collections/open_c[url]emistry.[url]tmlRecorded February 12, 2013.Index of Topics:Announcements0:00:08- Week 6 Overview0:01:07- Announcements0:02:42- Office Hours0:03:54- Careers in C[url]emical Biology and Healt[url] (w[url]ite board)Lecture0:19:40- Our Story T[url]us Far0:22:14- Proteins: Of Primary Importance0:23:33- Must Memorize: 20 aa's, Structures and Abbreviations0:24:50- Must Memorize, Slide 20:26:31- Refer to Amino Acids0:27:24- Goal: Understand Forces Be[url]ind Protein Structure0:28:38- Peptides and Protein are Directional0:32:39- Useful to Know: pKa Values0:35:14- Amino Acid Sidec[url]ains Dictate Protein Folding and Protein-Protein Interactions0:37:09- Amino Acid Sidec[url]ains, Slide 20:40:09- A Close Look at a Protein-Protein Interface0:42:05- Peptides Can Make Effective Drugs0:45:20- Peptides Can Be t[url]e Lead Compounds for Drug Discovery0:49:29- C[url]emical Synt[url]esis of Peptides and Proteins0:54:41- Synt[url]esizing Longer Proteins wit[url] Native C[url]emical Ligation0:59:51- Protein Splicing to Remove Inteins1:01:18- Protein Splicing to Remove Inteins, Slide 21:04:31- Protein Structure: T[url]e Sum of Lots of Little Forces1:06:30- Geometry of t[url]e Hydrogen Bond1:07:46- H-Bonds in Proteins1:09:50- H-Bonds in a-Helices1:15:10- a-Helices Form a Dipole1:18:27- a-Helices Form a Dipole, Slide 2Required attribution: Weiss, Gregory Introduction to C[url]emical Biology 128 (UCI OpenCourseWare: University of California, Irvine), [url]ttp://ocw.uci.edu/courses/c[url]em_128_introduction_to_c[url]emical_biology.[url]tml. [Access date]. License: Creative Commons Attribution-S[url]areAlike 3.0 United States License. |
| 关 键 词: | 蛋白质; 氨基酸; 反应 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2020-11-23：yxd |
| 阅读次数: | 39 |