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核壳纳米颗粒生物分子相互作用的剪裁及其在磁响应药物载体中的应用Tailoring biomolecular interactions of core-shell nanoparticles and their application to magnetoresponsive drug delivery vehicles |
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| 课程网址: | http://videolectures.net/biophysics2018_reimhult_nanoparticles/ |
| 主讲教师: | Erik Reimhult |
| 开课单位: | 自然资源与生命科学大学 |
| 开课时间: | 2018-07-09 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | Core-shell nanoparticles can be used in biomedical applications, e.g., as biomedical imaging contrast agents, for hyperthermia and in drug delivery, as well as for biotechnological applications such as separation and purification. Unique functions can be achieved by using nanoscale inorganic cores, such as superparamagnetic iron oxide nanocrystals for controlling interactions with magnetic fields. Using densely grafted polymer shells with controlled morphology and topology interactions with proteins can be tuned in biological fluids and we show this ultimately affects cell interaction and uptake. However, to enable advanced materials functions in a biological environment, e.g. specific binding, aggregation and drug release, integration of grafted stimuli-responsive polymer shells or into structured amphiphile and polymer assemblies must be carefully designed. |
| 关 键 词: | 核壳纳米颗粒; 生物医学应用; 纳米级无机磁芯 |
| 课程来源: | 视频讲座网 |
| 数据采集: | 2021-11-12：zkj |
| 最后编审: | 2021-11-12：zkj |
| 阅读次数: | 53 |