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第28讲-羰基反应的机理和平衡Lecture 28 - Mechanism and Equilibrium of Carbonyl Reactions |
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| 课程网址: | http://videolectures.net/yalespan125bs2011_mcbride_lec28/ |
| 主讲教师: | J. Michael McBride |
| 开课单位: | 耶鲁大学 |
| 开课时间: | 2014-08-19 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | This lecture aims at developing facility with devising plausible mechanisms for acid- and base-catalyzed reactions of carbonyl compounds, carboxylic acids, and their derivatives. When steric hindrance inhibits the A/D mechanism of Fischer esterification, an acid-catalyzed D/A mechanism can still occur. Substituent influence on the equilibrium constants for carbonyl hydration demonstrates four effects: bond strength, steric, electron withdrawal, and conjugation. Cyclic acetals play an important role in protecting the carbonyl groups of sugars, but acetals also can be used to protect alcohols, as can silyl ethers. Using amines instead of alcohols allows converting carbonyl compounds to imines via carbinolamines. |
| 关 键 词: | 羰基化合物; 酸碱催化反应; 环缩醛 |
| 课程来源: | 视频讲座网 |
| 数据采集: | 2021-11-19：zkj |
| 最后编审: | 2021-11-19：zkj |
| 阅读次数: | 73 |