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第10讲-生物分子工程:免疫工程(续)

Lecture 10 - Biomolecular Engineering: Engineering of Immunity (cont.)
课程网址: http://videolectures.net/yalebeng100s08_saltzman_lec10/  
主讲教师: W. Mark Saltzman
开课单位: 耶鲁大学
开课时间: 2011-01-04
课程语种: 英语
中文简介:

Saltzman教授继续他关于疫苗主题的演讲。首先,Saltzman教授描述了宿主对病原体识别的免疫反应,包括免疫球蛋白释放、T细胞激活和记忆细胞生成。讨论了索尔克脊髓灰质炎疫苗和现代口服脊髓灰质炎疫苗的生产、分销和制造过程中面临的挑战。萨尔茨曼教授接着谈到了可用于生产疫苗的一系列生物工程方法:减毒疫苗、亚单位疫苗和基于DNA的疫苗。最后,将疫苗的生命干预成本分析(每挽救一个人生命的技术成本)与其他政策进行了比较,以进一步强调疫苗对改善全世界公共卫生的影响。
课程简介: Professor Saltzman continues his presentation on the topic of vaccine. First, Professor Saltzman describes the host immune response to pathogen recognition, in terms of immunoglobulin release, T-cell activation, and memory cell production. The production, distribution, and challenges involved in making of the Salk polio vaccine and the modern, oral polio vaccine are discussed. Professor Saltzman then talks about the range of bioengineering approaches that can be used to produce vaccine: attenuated, subunit, and DNA-based. Finally, a life-intervention cost analysis (cost of technology per human life saved) for vaccine was compared to other policies to further emphasize the impact of vaccine on improving public health worldwide.  
关 键 词: 疫苗; 免疫反应; 现代口服脊髓灰质炎疫苗
课程来源: 视频讲座网
数据采集: 2021-11-28:zkj
最后编审: 2021-11-28:zkj
阅读次数: 78