图 书 馆
第11讲-生物分子工程：一般概念Lecture 11 - Biomolecular Engineering: General Concepts |
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| 课程网址: | http://videolectures.net/yalebeng100s08_saltzman_lec11/ |
| 主讲教师: | W. Mark Saltzman |
| 开课单位: | 耶鲁大学 |
| 开课时间: | 2011-01-04 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | Professor Saltzman starts the lecture with an introduction to pharmacokinetics and pharmacodynamics. Professor Saltzman talks about the concept of dose-response. He introduces different routes of drug administration and how they affect drug distribution and bioavailability (i.e., intravenous, oral, and sublingual routes). First-pass drug metabolism by the liver is also identified as an important source of drug degradation. Finally, modeling the body as a well-stirred vessel, Professor Saltzman explains the first-order rate equation: C = (M0/V)*e-kt, that can be used calculate the amount of drug in the body (M) as a function of time (t) and a rate constant (k); and the equation for drug half-life: t = ln(2/k). |
| 关 键 词: | 药代动力学; 药效学; 剂量反应 |
| 课程来源: | 视频讲座网 |
| 数据采集: | 2021-11-28：zkj |
| 最后编审: | 2021-11-28：zkj |
| 阅读次数: | 57 |