图 书 馆
第12讲-生物分子工程：一般概念（续）Lecture 12 - Biomolecular Engineering: General Concepts (cont.) |
|
| 课程网址: | http://videolectures.net/yalebeng100s08_saltzman_lec12/ |
| 主讲教师: | W. Mark Saltzman |
| 开课单位: | 耶鲁大学 |
| 开课时间: | 2011-01-04 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | Professor Saltzman reviews the pharmacokinetic first-order rate equation that can be used to model changes in drug concentration in the blood, as well as its derivation from the law of conservation of mass. The importance of maintaining a drug concentration that is sufficient for therapeutic purpose, but below a toxic level, is emphasized. Since this is directly affected by drug administration method, ways to localize and sustain therapeutic concentrations of drug, such as incorporating in slow-releasing, biocompatible polymers are introduced. Professor Saltzman gave some examples of clinical applications of controlled release drug delivery system, such as anti-restenosis drug incorporated into stents, and chemotherapeutic drugs in brain implants and microspheres. |
| 关 键 词: | 药代动力学一级速率方程; 血液中药物浓度; 控释药物释放系统 |
| 课程来源: | 视频讲座网 |
| 数据采集: | 2021-11-28：zkj |
| 最后编审: | 2021-11-28：zkj |
| 阅读次数: | 58 |