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对空间结构种群的遗传学进行建模

Modelling the genetics of spatially structured populations
课程网址: http://videolectures.net/8ecm2021_etheridge_genetics_spatially/  
主讲教师: Alison Etheridge
开课单位: 牛津大学
开课时间: 2021-07-06
课程语种: 英语
中文简介:
上个世纪,遗传数据的性质和规模以及研究它们的工具有了显着的发展。 尽管如此,基本问题仍未得到解答。 种群的遗传组成可以通过自然选择、突变、交配以及其他遗传和进化机制来改变。 这些机制的效果,以及它们相互作用的方式,也受到人口空间结构的影响。 寻找足够的数学模型来研究进化力和空间结构之间的相互作用仍在进行中。 以具有生物学意义的方式捕捉随机效应尤其具有挑战性。 在本次演讲中,我们将探讨已经取得的一些进展,以及剩余的一些挑战。
课程简介: The last century has seen remarkable developments in the nature and scale of genetic data, and the tools with which to interrogate them. Nonetheless fundamental questions remain unanswered. The genetic composition of a population can be changed by natural selection, mutation, mating, and other genetic and evolutionary mechanisms. The effect of these mechanisms, and the way in which they interact with one another, is also influenced by the spatial structure of the population. The hunt for adequate mathematical models with which to investigate the interaction between the forces of evolution and spatial structure is still very much in progress. Capturing stochastic effects in a biologically meangingful way is particularly challenging. In this talk we shall explore some of the progress that has been made, and some of the remaining challenges.
关 键 词: 空间结构; 数学模型; 遗传学
课程来源: 视频讲座网
数据采集: 2022-03-27:hqh
最后编审: 2022-03-27:hqh
阅读次数: 32