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表观遗传学和地貌

Epigenomics and Morphodynamics
课程网址: http://videolectures.net/eccs08_kepes_eam/  
主讲教师: François Képès
开课单位: 巴黎科技公司
开课时间: 2008-10-17
课程语种: 英语
中文简介:
遗传基质DNA在化学上相当惰性。但是,它具有指定生物体形式的信息要素之一。如何从DNA开始指定表格?最近的观察表明转录的动力学 - mdash;解码遗传信息的过程—可以将某种拓扑类的形式印在DNA上。该拓扑结构允许优化转录并促进响应于环境修饰的转录状态的协同变化。据我们所知,这种形态发生事件首先发生在从DNA到生物体的路径上。
课程简介: The substrate for heredity, DNA, is chemically rather inert. However, it bears one of the elements of information that specify the form of the organism. How can a form be specified, starting from DNA ? Recent observations indicate that the dynamics of transcription — the process that decodes the hereditary information — can imprint forms of a certain topological class onto DNA. This topology allows both to optimize transcription and to facilitate the concerted change of the transcriptional status in response to environmental modifications. To the best of our knowledge, this morphogenetic event is first on the path from DNA to organism.
关 键 词: 遗传; 底物DNA; 构成元素; DNA拓扑
课程来源: 视频讲座网
最后编审: 2020-06-06:liush
阅读次数: 49