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寻找创新生物药物

Searching for innovative biological drugs
课程网址: http://videolectures.net/icgeb_zacchigna_innovative_biological_dr...  
主讲教师: Serena Zacchigna
开课单位: 国际遗传工程和生物技术中心
开课时间: 2019-06-28
课程语种: 英语
中文简介:
非传染性疾病(NCD),也称为慢性病,往往持续时间较长,是遗传、生理、环境和行为因素综合作用的结果。非传染性疾病的主要类型为变性疾病,包括心血管疾病(如心脏病发作和中风)、癌症、慢性呼吸道疾病(如慢性阻塞性肺病和哮喘)和糖尿病。这四类疾病占全世界死亡人数的80%以上。这些疾病的复杂性限制了传统药物的疗效,并促使开发能够干扰复杂生物过程的创新生物疗法。筛选策略,尤其是基于功能读数的高通量筛选,正在成为在特定生物背景下识别最有效分子的宝贵工具,为开发治疗慢性、退行性非传染性疾病的创新生物疗法铺平了道路。
课程简介: Noncommunicable diseases (NCDs), also known as chronic diseases, tend to be of long duration and are the result of a combination of genetic, physiological, environmental and behavioral factors. The main types of NCDs are degenerative in nature and include cardiovascular diseases (like heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma) and diabetes. These four groups of diseases account for over 80% of all deaths worldwide. The complexity of these diseases limits the efficacy of traditional drugs and urges the development of innovative, biological therapies able to interfere with complex biological processes. Screening strategies, and in particular high throughout screening based on functional readouts, are emerging as precious tools to identify the most potent molecules in a specific biological context, paving the way to the development of innovative biotherapeutics for the treatment of chronic, degenerative, NCDs.
关 键 词: 寻找创新生物药物; 数据科学; 非传染性疾病(NCD); 创新生物疗法; 创新生物疗法
课程来源: 视频讲座网
数据采集: 2022-10-14:cyh
最后编审: 2022-10-14:cyh
阅读次数: 20