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4讲:癌症干细胞

Lecture 4: Cancer and Stem Cells
课程网址: http://videolectures.net/epigenetics2010_cedar_lec04/  
主讲教师: Howard Cedar
开课单位: 耶路撒冷希伯来大学
开课时间: 2010-08-18
课程语种: 英语
中文简介:
Cedar教授解释了DNA甲基化在癌症和干细胞中的作用。虽然最初许多人认为在癌症中DNA甲基化较少,但事实证明并非如此简单。 Cedar博士展示了大量的实验和假设,展示了每种组织和癌症类型的不同之处。此外,他还证明了哪些因素对癌症中表观遗传信号的调节具有重要意义。此外,他通过显示许多调节途径相似并与分化相关联,将癌症中甲基化的调节与干细胞调节联系起来。
课程简介: Professor Cedar explains the role of DNA methylation in cancer and stem cells. While initially many people thought that in cancer there was less DNA methylation, it turns out not to be so simple. Presenting a serious of experiments and hypotheses, Dr. Cedar shows how each tissue and cancer type are different. Moreover, he demonstrates which factors are important in the regulation of epigenetic signaling in cancer. Additionally, he connects the regulation of methylation in cancer to stem cell regulation by showing that many of the regulatory pathways are similar and are connected to differentiation.
关 键 词: 癌症; 干细胞DNA甲基化; 表观遗传信号调控; 干细胞分化调控
课程来源: 视频讲座网
最后编审: 2020-10-14:yumf
阅读次数: 61