图 书 馆
通过时间感知 LSTM 网络进行患者子类型分析Patient Subtyping via Time-Aware LSTM Network |
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| 课程网址: | http://videolectures.net/kdd2017_baytas_patient_subtyping/ |
| 主讲教师: | Inci M. Baytas |
| 开课单位: | 密歇根州立大学 |
| 开课时间: | 2017-10-09 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | In the study of various diseases, heterogeneity among patients usually leads to different progression patterns and may require different types of therapeutic intervention. Therefore, it is important to study patient subtyping, which is grouping of patients into disease characterizing subtypes. Subtyping from complex patient data is challenging because of the information heterogeneity and temporal dynamics. Long-Short Term Memory (LSTM) has been successfully used in many domains for processing sequential data, and recently applied for analyzing longitudinal patient records. The LSTM units are designed to handle data with constant elapsed times between consecutive elements of a sequence. Given that time lapse between successive elements in patient records can vary from days to months, the design of traditional LSTM may lead to suboptimal performance. In this paper, we propose a novel LSTM unit called Time-Aware LSTM (T-LSTM) to handle irregular time intervals in longitudinal patient records. We learn a subspace decomposition of the cell memory which enables time decay to discount the memory content according to the elapsed time. We propose a patient subtyping model that leverages the proposed T-LSTM in an auto-encoder to learn a powerful single representation for sequential records of patients, which are then used to cluster patients into clinical subtypes. Experiments on synthetic and real world datasets show that the proposed T-LSTM architecture captures the underlying structures in the sequences with time irregularities. |
| 关 键 词: | 合成数据集; 长短期记忆; 数据科学 |
| 课程来源: | 视频讲座网 |
| 数据采集: | 2023-12-26：wujk |
| 最后编审: | 2023-12-26：wujk |
| 阅读次数: | 28 |