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单分子成像:捕获纳米级细胞机器

Single-Molecule Imaging: Capturing Nanoscale Cellular Machines In Action
课程网址: https://ocw.mit.edu/courses/7-343-single-molecule-imaging-capturi...  
主讲教师: Dr. Hazal B. Kose
开课单位: 麻省理工学院
开课时间: 2021-01-01
课程语种: 英语
中文简介:
你知道吗,我们的细胞中大约有 2 米长的 DNA,直径小于 10 μm?或者说,为了复制DNA,它被一种协调至少六种不同酶的细胞装置以每秒70,000个碱基对的速度复制?或者微管形成超过1米长的“铁路”,分子机器在神经细胞内运输货物?在本课程中,我们将探讨单分子成像技术如何捕获实时工作的巨型细胞机器。 本课程是麻省理工学院生物系提供的众多高级本科研讨会之一。这些研讨会是为有兴趣使用主要研究文献在高度互动的环境中讨论和了解当前生物学研究的学生量身定制的。高级本科生研讨会的许多讲师都是对教学有浓厚兴趣的博士后科学家。
课程简介: Did you know that we have approximately 2 meters of DNA packed in our cells, which are less than 10 μm diameter? Or that to replicate DNA it is copied at a rate of 70,000 basepairs per second by a cellular apparatus that coordinates at least six different enzymes? Or that microtubules form greater than 1 meter long “railways” upon which molecular machines transport cargo within nerve cells? In this course, we will explore how single-molecule imaging techniques capture the mega-cellular machines working in real-time. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
关 键 词: 单分子成像; 细胞机器; 实时工作
课程来源: 麻省理工学院公开课
数据采集: 2024-02-18:chenjy
最后编审: 2024-02-18:chenjy
阅读次数: 11