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7.346干扰:在生物学和治疗的革命(麻省理工学院)

7.346 RNAi: A Revolution in Biology and Therapeutics (MIT)
课程网址: http://ocw.mit.edu/courses/biology/7-346-rnai-a-revolution-in-bio...  
主讲教师: Allan Gurtan ; Michael Goldberg
开课单位: 麻省理工学院
开课时间: 2010-01-01
课程语种: 英语
中文简介:
尽管经过了几个世纪的努力,现代医学仍在努力寻找疾病的根源并提供无副作用的特定治疗。传统的小分子和基于蛋白质的治疗方法都取得了有限的成功。下一个治疗前沿是什么?答案可能是RNA干扰。在本课程中,我们将重点关注RNAi的治疗潜力。我们将讨论其在正常生物过程中的发现功能,作为实验工具的实用性,治疗用途的潜力以及生物技术行业的追求。本课程是麻省理工学院生物系提供的许多高级本科研讨会之一。这些研讨会专为有兴趣使用初级研究文献的学生量身定制,以便在高度互动的环境中讨论和了解当前的生物学研究。高级本科生研讨会的许多讲师都是博士后科学家,他们对教学非常感兴趣。
课程简介: Despite centuries of effort, modern medicine still struggles to find the source of disease and to provide specific treatment without side effects. Both traditional small molecules and protein-based therapeutics have achieved only limited success. What is the next therapeutic frontier? The answer may be RNA interference. In this course, we will focus on the therapeutic potential of RNAi. We will discuss its discovery functions in normal biological processes, utility as an experimental tool, potential for therapeutic use, and pursuit by the biotechnology industry. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
关 键 词: RNA; RNA接口; 治疗; siRNA; miRNA; shRNA; 生物学
课程来源: 麻省理工学院公开课
最后编审: 2020-10-14:yumf
阅读次数: 53