0


在雷达屏幕上的错误:如何欺骗我们的免疫防御系统

Under the Radar Screen: How Bugs Trick Our Immune Defenses
课程网址: http://ocw.mit.edu/courses/biology/7-340-under-the-radar-screen-h...  
主讲教师: Gijsbert Grotenbreg; Marie-Eve Paquet
开课单位: 麻省理工学院
开课时间: 2007-01-01
课程语种: 英语
中文简介:
在本课程中,我们将探讨微生物击败我们免疫系统的具体方式以及受到攻击的分子机制(吞噬作用,泛素/蛋白酶体途径,MHC I / II抗原呈递)。通过我们对主要研究文献的讨论和剖析,我们将探讨宿主 - 病原体相互作用的各个方面。我们将特别强调该领域使用的实验技术以及如何阅读和理解研究数据。通过具体的例子,还将讨论与微生物作斗争的技术进步。本课程是麻省理工学院生物系提供的许多高级本科研讨会之一。这些研讨会专为有兴趣使用初级研究文献的学生量身定制,以便在高度互动的环境中讨论和了解当前的生物学研究。高级本科生研讨会的许多讲师都是博士后科学家,他们对教学非常感兴趣。
课程简介: In this course, we will explore the specific ways by which microbes defeat our immune system and the molecular mechanisms that are under attack (phagocytosis, the ubiquitin/proteasome pathway, MHC I/II antigen presentation). Through our discussion and dissection of the primary research literature, we will explore aspects of host-pathogen interactions. We will particularly emphasize the experimental techniques used in the field and how to read and understand research data. Technological advances in the fight against microbes will also be discussed, with specific examples. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
关 键 词: 免疫系统; ,泛素/蛋白酶体途径; MHCⅠ/Ⅱ抗原呈递; 沙门氏菌; 病原相关分子模式; PAMP
课程来源: 麻省理工学院公开课
最后编审: 2020-10-21:yumf
阅读次数: 54