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当发展出现问题时:癌症如何选择胚胎发生机制

When Development Goes Awry: How Cancer Co-opts Mechanisms of Embryogensis
课程网址: http://ocw.mit.edu/courses/biology/7-343-when-development-goes-aw...  
主讲教师: Etienne Meylan; Trudy Oliver
开课单位: 麻省理工学院
开课时间: 2009-01-01
课程语种: 英语
中文简介:
在本课程中,我们将研究癌症与正常发育之间的相似性,以了解肿瘤如何选择正常的发育过程以促进癌症的发生,维持和进展。我们将研究控制这些过程的关键信号传导途径,重要的是,这些途径中的一些如何成为癌症治疗的治疗靶点。我们将讨论未来的治疗方法如何针对特定患者的癌细胞进行个性化定制。我们还将考虑新批准的药物的例子,这些药物可以帮助患者对抗这种破坏性疾病。本课程是麻省理工学院生物系提供的许多高级本科研讨会之一。这些研讨会专为有兴趣使用初级研究文献的学生量身定制,以便在高度互动的环境中讨论和了解当前的生物学研究。高级本科生研讨会的许多讲师都是博士后科学家,他们对教学非常感兴趣。
课程简介: During this course, we will study the similarities between cancer and normal development to understand how tumors co-opt normal developmental processes to facilitate cancer initiation, maintenance and progression. We will examine critical signaling pathways that govern these processes and, importantly, how some of these pathways hold promise as therapeutic targets for cancer treatment. We will discuss how future treatments might be personalized to target cancer cells in specific patients. We will also consider examples of newly-approved drugs that have dramatically helped patients combat this devastating disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
关 键 词: 导通路; 癌细胞; 致命疾病
课程来源: 麻省理工学院公开课
最后编审: 2020-10-21:yumf
阅读次数: 44