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RNAi:在生物学和疗法的革命

RNAi: A Revolution in Biology and Therapeutics
课程网址: http://ocw.mit.edu/courses/biology/7-346-rnai-a-revolution-in-bio...  
主讲教师: Allan Gurtan; Michael Goldberg
开课单位: 麻省理工学院
开课时间: 2010-01-01
课程语种: 英语
中文简介:
尽管经过几个世纪的努力, 现代医学仍在努力寻找疾病的来源, 并在没有副作用的情况下提供具体治疗。传统的小分子和蛋白质为基础的疗法只取得了有限的成功。下一个治疗前沿是什么?答案可能是 rna 干扰。在本课程中, 我们将重点讨论 rnai 的治疗潜力。我们将讨论它在正常生物过程中的发现功能、作为实验工具的效用、治疗用途的潜力以及生物技术产业的追求。本课程是麻省理工学院生物系提供的众多高级本科生研讨会之一。这些研讨会是为有兴趣利用初级研究文献在高度互动的环境中讨论和了解当前生物研究的学生量身定制的。高级本科生研讨会的许多教员都是对教学有浓厚兴趣的博士后科学家。
课程简介: Despite centuries of effort, modern medicine still struggles to find the source of disease and to provide specific treatment without side effects. Both traditional small molecules and protein-based therapeutics have achieved only limited success. What is the next therapeutic frontier? The answer may be RNA interference. In this course, we will focus on the therapeutic potential of RNAi. We will discuss its discovery functions in normal biological processes, utility as an experimental tool, potential for therapeutic use, and pursuit by the biotechnology industry. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
关 键 词: RNA干扰; 生物技术产业; 治疗潜力
课程来源: 麻省理工学院公开课
最后编审: 2020-10-21:yumf
阅读次数: 50