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7.90j计算功能基因组学(麻省理工学院)

7.90J Computational Functional Genomics (MIT)
课程网址: http://ocw.mit.edu/courses/biology/7-90j-computational-functional...  
主讲教师: Gifford, David, Jaakkola, Tommi
开课单位: 麻省理工学院
开课时间: 2005-03-01
课程语种: 英语
中文简介:
该课程着重于用计算术语来描述系统生物学和功能基因组学中的当代问题,并提供适当的工具和方法来解决它们。主题包括基因组结构和功能,转录调控,特别是干细胞生物学;测量技术,如微阵列(表达,蛋白质-DNA相互作用,染色质结构);统计数据分析,预测和因果推断以及实验设计。重点是将问题结构(生物学问题)与适当的计算方法联系起来。
课程简介: The course focuses on casting contemporary problems in systems biology and functional genomics in computational terms and providing appropriate tools and methods to solve them. Topics include genome structure and function, transcriptional regulation, and stem cell biology in particular; measurement technologies such as microarrays (expression, protein-DNA interactions, chromatin structure); statistical data analysis, predictive and causal inference, and experiment design. The emphasis is on coupling problem structures (biological questions) with appropriate computational approaches.
关 键 词: 系统生物学; 基因组结构; 基因组序列; 误差模型; 表型; 聚类
课程来源: 麻省理工学院公开课
最后编审: 2021-10-09:nkq
阅读次数: 31