图 书 馆
生物网络监督重建Supervised reconstruction of biological networks |
|
| 课程网址: | http://videolectures.net/mlsb07_vert_srb/ |
| 主讲教师: | Jean-Philippe Vert |
| 开课单位: | 国立巴黎高等矿业学院 |
| 开课时间: | 2007-11-20 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | The inference or reconstruction of various biological networks, including regulatory, signalling or metabolic pathways, from large-scale heterogeneous data is currently an active research subject with several important applications in systems biology. While several approaches proposed so far cast this problem as inferring a graph de novo from genomic data, I will argue in this talk that the network of interest is often partially known and that the reconstruction process should use this partial knowledge to guide the inference of the missing edges. I will then review how this paradigm leads naturally to various supervised machine learning algorithms for graph inference, and illustrate the relevance of the approach through several examples of successful prediction of missing enzymes in metabolic networks. |
| 关 键 词: | 生物信息学; 计算系统生物学; 生物网络 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2020-06-29：yumf |
| 阅读次数: | 57 |