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生物信息学和计算生物学解决方案使用R和Bioconductor

Bioinformatics and Computational Biology Solutions Using R and Bioconductor
课程网址: http://ocw.jhsph.edu/courses/BioinformaticsComputationalBiology/  
主讲教师: Rafael Irizarry
开课单位: 布隆博格公共卫生学院
开课时间: 信息不详。欢迎您在右侧留言补充。
课程语种: 英语
中文简介:
本课程涵盖R软件的基础知识和生物导体项目(一个广泛使用的开放源代码和开放开发软件项目,用于分析和理解基因组学和分子生物学的高通量实验产生的数据,并植根于开放源代码统计计算环境R)的关键能力。包括从微阵列和其他平台导入和预处理高通量数据。还介绍了解释和批判性评价生物信息学和计算生物学文献所必需的统计概念和工具。包括预处理和规范化、统计推断、多重比较校正、多重比较背景下的贝叶斯推理、聚类和分类/机器学习的概述。
课程简介: This course covers the basics of R software and the key capabilities of the Bioconductor project (a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology and rooted in the open source statistical computing environment R), including importation and preprocessing of high-throughput data from microarrays and other platforms. Also introduces statistical concepts and tools necessary to interpret and critically evaluate the bioinformatics and computational biology literature. Includes an overview of of preprocessing and normalization, statistical inference, multiple comparison corrections, Bayesian Inference in the context of multiple comparisons, clustering, and classification/machine learning.
关 键 词: 生物信息学; 计算生物学; 聚类
课程来源: 布隆博格公共卫生学院公开课
最后编审: 2016-04-22:cmh
阅读次数: 24