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三方面假设检验：同时检验自傲、自信和自卑Three-sided Hypothesis Testing: Simultaneous Testing of Superiority, Equivalence and Inferiority |
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| 课程网址: | http://videolectures.net/as2010_goeman_tsh/ |
| 主讲教师: | Jelle Goeman |
| 开课单位: | 莱顿大学 |
| 开课时间: | 2010-10-11 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | We propose three-sided testing, a testing framework for simultaneous testing of inferiority, equivalence and superiority in clinical trials, controlling for multiple testing using the partitioning principle. Like the usual two-sided testing approach, this approach is completely symmetric in the two treatments compared. Still, because the hypotheses of inferiority and superiority are tested with one-sided tests, the proposed approach has more power than the two-sided approach to infer non-inferiority or non-superiority. Applied to the classical point null hypothesis of equivalence, the three sided testing approach shows that it is sometimes possible to make an inference on the sign of the parameter of interest, even when the null hypothesis itself could not be rejected. Relationships with confidence intervals are explored, and the effectiveness of the three-sided testing approach is demonstrated in a number of recent clinical trials. |
| 关 键 词: | 心理学; 临床医学; 测试 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2020-03-23：chenxin |
| 阅读次数: | 63 |