生物信号网络的另一种建模方法An alternative modeling for biological signaling networks |
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课程网址: | http://videolectures.net/acs07_fernandez_bsn/ |
主讲教师: | Roberto Fernández |
开课单位: | 鲁昂大学 |
开课时间: | 2007-12-17 |
课程语种: | 英语 |
中文简介: | 生物信号网络传输和处理细胞外信息,触发复杂的转换,导致不同的细胞反应。微分方程很好地掌握了细胞的整体行为;我们面临的挑战是建立数学上可负担得起的微观模型,从而得出这些方程。传统的基于化学动力学的建模方法受到大量假设的阻碍。作为一种替代,我们提出了由非对称平均场相互作用定义的自旋反转动力学。这种动力学产生密度剖面过程,其轨迹几乎必然收敛于具有复杂行为的动力系统的解。 |
课程简介: | Biological signaling networks transmit and process extra-cellular information, triggering complex transformations that lead to different cellular responses. The overall cellular behavior is well grasped by differential equations; the challenge is to produce mathematically affordable microscopic models leading to these equations. The usual modeling approach, based on chemical kinetics, is hampered by the large number of assumptions needed. As an alternative, we propose a spin-flip dynamics defined by asymmetric mean-field interactions. This dynamics yield density-profile processes whose trajectories converge almost surely to the solutions of dynamical systems with possibly complex behavior. |
关 键 词: | 生物信号网络; 建模 |
课程来源: | 视频讲座网 |
最后编审: | 2019-11-01:lxf |
阅读次数: | 44 |