BioBayes:系统生物学的贝叶斯推论BioBayes: Bayesian inference for Systems Biology |
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课程网址: | http://videolectures.net/licsb08_vyshemirsky_bbi/ |
主讲教师: | Vladislav Vyshemirsky |
开课单位: | 格拉斯哥大学 |
开课时间: | 2008-04-17 |
课程语种: | 英语 |
中文简介: | 生化系统建模涉及多个层次的不确定性。例如,实验数据通常包含大量的观察结果错误,并且可能存在关于所研究的过程的替代假设现象。贝叶斯推理的方法提供了一致的框架在不确定条件下建模和预测。 我们提供了一个软件包,将贝叶斯推理方法应用于系统生物学中的问题。该软件包名为BioBayes,它提供了参数框架,估计和证据假设测试定义的生化系统模型使用常微分方程。 该软件基于模块化架构,允许插入第三方方法和扩展。 |
课程简介: | There are several levels of uncertainty involved in modelling biochemical systems. For example, the experimental data usually contains considerable amount of observation errors, and there may be alternative hypotheses about the processes involved in studied phenomena. The methods of Bayesian inference provide a consistent framework for modelling and predicting in uncertain conditions. We present a software package for applying Bayesian inferential methodology to problems in Systems Biology. This software package is named BioBayes, and it provides a framework for parameter estimation and evidential hypotheses testing over models of biochemical systems defined using ordinary differential equations. The software is based on modular architecture and allows plugging-in third party methods and extensions. |
关 键 词: | 生化系统建模; 替代假设现象; 贝叶斯推理 |
课程来源: | 视频讲座网 |
最后编审: | 2021-12-22:liyy |
阅读次数: | 86 |