图 书 馆
用碎片-凝固过程模拟遗传变异Modelling Genetic Variations with Fragmentation-Coagulation Processes |
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| 课程网址: | http://videolectures.net/nips2011_teh_fragmentation/ |
| 主讲教师: | Yee Whye Teh |
| 开课单位: | 牛津大学 |
| 开课时间: | 2012-01-25 |
| 课程语种: | 英语 |
| 中文简介: |  |
| 课程简介: | We propose a novel class of Bayesian nonparametric models for sequential data called fragmentation-coagulation processes (FCPs). FCPs model a set of sequences using a partition-valued Markov process which evolves by splitting and merging clusters. An FCP is exchangeable, projective, stationary and reversible, and its equilibrium distributions are given by the Chinese restaurant process. As opposed to hidden Markov models, FCPs allow for flexible modelling of the number of clusters, and they avoid label switching non-identifiability problems. We develop an efficient Gibbs sampler for FCPs which uses uniformization and the forward-backward algorithm. Our development of FCPs is motivated by applications in population genetics, and we demonstrate the utility of FCPs on problems of genotype imputation with phased and unphased SNP data. |
| 关 键 词: | 贝叶斯非参数模型; 碎裂凝固过程; 马尔可夫过程 |
| 课程来源: | 视频讲座网 |
| 最后编审: | 2019-09-06：lxf |
| 阅读次数: | 39 |