图 书 馆
测量双聚类中移位和缩放模式的质量Measuring the Quality of Shifting and Scaling Patterns in Biclusters |
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| 课程网址: | http://videolectures.net/prib2010_pontes_mqss/ |
| 主讲教师: | Beatriz Pontes Balanza |
| 开课单位: | 塞维利亚大学 |
| 开课时间: | 2014-10-14 |
| 课程语种: | 英语 |
| 中文简介: |  在这项工作中，我们通过进化计算解决了基因表达数据的聚类问题，事实证明该方法在复杂问题上具有出色的表现。在表达数据分析中，最重要的目标可能不是找到最大的双簇，因为找到一组在一定条件下表现出相似行为的基因可能更有趣。我们的方法基于进化算法，并按照顺序覆盖策略搜索双聚类。另外，我们特别注意寻找变化较大的高质量双楔座这一事实。通过酵母和结肠癌数据集的分析，讨论了我们的方法发现的二聚体的质量。 |
| 课程简介: | In this work, we address the biclustering of gene expression data with evolutionary computation, which has been proven to have excellent performance on complex problems. In expression data analysis, the most important goal may not be finding the maximum bicluster, as it might be more interesting to find a set of genes showing similar behavior under a set of conditions. Our approach is based on evolutionary algorithms and searches for biclusters following a sequential covering strategy. In addition, we pay special attention to the fact of looking for high quality biclusters with large variation. The quality of biclusters found by our approach is discussed by means of the analysis of yeast and colon cancer datasets. |
| 关 键 词: | 基因表达数据; 数据集 |
| 课程来源: | 视频讲座网 |
| 数据采集: | 2021-04-14：zyk |
| 最后编审: | 2021-04-14：zyk |
| 阅读次数: | 46 |