开课单位--雪菲尔大学
1 1/1

1
Bringing gene therapy based SOD1 silencing towards human trials: A highly efficacious, off-target free and biomarker supported strategy for fALS[将基于基因治疗的SOD1沉默引入人体试验:一种高效、无靶点和生物标记物支持的fALS策略]
   Joseph M. Scarrott(雪菲尔大学) Aims: 1. To evaluate the therapeutic efficacy of scAAV9-shRNA mediated SOD1 silencing in the SOD1-G93A mouse model using a clinic ready vector. 2. To ...
热度:42

2
C9orf 72 interacts with coilin and influences Cajal body dynamics and splicing[C9orf 72与coilin相互作用并影响Cajal体动力学和剪接]
   Yolanda Gibson(雪菲尔大学) Rationale & Hypothesis: The GGGGCC hexanucleotide repeat expansion in the C9orf72 gene is the leading cause of amyotrophic lateral sclerosis (ALS)...
热度:50

3
Clinical, pathological and molecular characterisation of C9orf72-ALS leads to identification of novel therapeutic targets[C9orf72 ALS的临床、病理和分子特征导致新的治疗靶点的确定]
  Johnathan Cooper-Knock(雪菲尔大学) Johnathan Cooper-Knock works as a clinical research fellow at SITRAN, the Sheffield Institute for Translational Neuroscience in Sheffield, UK. His int...
热度:44

4
Probabilistic Approaches for Computational Biology and Medicine[计算生物学和医学的概率方法]
  Neil D. Lawrence(雪菲尔大学) In this talk we will introduce probabilistic approaches to challenges in computational biology and personalized medicine based on Gaussian process mod...
热度:43

5
Gene expression profiling in ALS: past, present and future[ALS的过去和未来:基因表达谱]
  Janine Kirby(雪菲尔大学) Gene expression profiling has come a long way since the term was first widely used in the mid to late 1990’s. With the advent of microarrays all...
热度:62

6
Deep Gaussian processes[深高斯过程]
  Neil D. Lawrence(雪菲尔大学) In this paper we introduce deep Gaussian process (GP) models. Deep GPs are a deep belief network based on Gaussian process mappings. The data is model...
热度:123

7
HLT and ML for the Semantic Web[语义网的HLT和MLT]
  Fabio Ciravegna(雪菲尔大学) This is a one-hour video recording of the presentation of Fabio Ciravegna at the KnowledgeWeb summer school 2007. It comprises the video synchronized ...
热度:84
1 1/1